Principal Scientist, Process Chemistry

Job Description

Our client, a global CDMO, is looking to add a Principal Scientist, Process Chemistry to their research and development team. As a member of process R&D, the qualified candidate will develop and execute a work plan for synthesis of a small molecule; then conduct hands on chemical process research and development, report results, and support GXP manufacturing of that molecule.

Key Responsibilities:

• Plan, develop, and safely execute existing chemical processes to support GXP manufacturing of small molecules – up to and including Active Pharmaceutical Ingredients.
• Propose, develop, and implement new synthetic routes.
• Propose, develop, and implement improved reaction, purification, and isolation conditions.
• Routinely demonstrate scientific initiative and creativity in research and development activities to solve problems and resolve project hurdles.
• Employ effective writing and oral presentation skills to communicate experimental results and project reports with the project team, management, and clients.
• Build strong relationships with peers and cross functional teams to enable high productivity.

Qualifications:

• PhD Degree in Organic Chemistry with 8+ years of experience (preferably in the pharmaceutical industry, or closely related sector).
• A broad range of expertise in modern synthetic organic chemistry, and/or biocatalysis, purification, instrumentation (LC/GC, LC/GC-MS, NMR, DSC, etc.).
• Any of the following traits is a plus:
  • Experience in multistep synthesis of organic molecules
  • Experience with Design of Experiment (DoE)
  • Experience with flow chemistries
  • Experience with cGMP production